本文介绍如何使用VCFtools过滤质量低于20且读取深度小于20的单核苷酸多态性（SNPs），这些被认为是低质量的SNP调用。通过使用vcf-annotate命令，可以有效地过滤掉这些低质量的数据。
VCFtools provide a wide range of functionality for the filtering, analysis and transformation of vcf files. Typically, SNPs of quality < 20 and read depth < 20 are filtered out as they are considered low quality SNP calls. This can be done in VCFtools by using vcf-annotate command as follows:
cat file.vcf | vcf-annotate --filter Qual=20/MinDP=20 > file-filtered.vcf
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