python-ProDy

Preface:优快云博客突然打不开了，转到博客园来好了。最近在上生物信息学，查找工具的时候看到python的一个包ProDy，记录下来。

prody包官网介绍：http://prody.csb.pitt.edu/

ProDy Project

ProDy is a free and open-source Python package for protein structural dynamics analysis. It is designed as a flexible and responsive API suitable for interactive usage and application development.

在bioinformatics期刊上有一篇介绍的文章：http://bioinformatics.oxfordjournals.org/content/27/11/1575

Abstract如下：

Summary: We developed a Python package, ProDy, for structure-based analysis of protein dynamics. ProDy allows for quantitative characterization of structural variations in heterogeneous datasets of structures experimentally resolved for a given biomolecular system, and for comparison of these variations with the theoretically predicted equilibrium dynamics. Datasets include structural ensembles for a given family or subfamily of proteins, their mutants and sequence homologues, in the presence/absence of their substrates, ligands or inhibitors. Numerous helper functions enable comparative analysis of experimental and theoretical data, and visualization of the principal changes in conformations that are accessible in different functional states. ProDyapplication programming interface (API) has been designed so that users can easily extend the software and implement new methods.

转载于:https://www.cnblogs.com/yuebu/p/4335569.html