SRC-1作为类固醇受体共激活剂，具有组蛋白乙酰转移酶活性，参与染色质乙酰化和基因转录调控。该文揭示SRC-1与PCAF相互作用，通过乙酰化DNA结合的组蛋白，促进特定基因的表达，提供了一种理解转录因子如何克服染色质抑制的机制。
Steroid receptor coactivator-1 is a histone acetyltransferase
Nature volume 389, pages 194–198 (11 September 1997)
类固醇受体共激活剂-1（SRC-1）是组蛋白乙酰转移酶
主要名词：
P300/CBP-associated factor (PCAF), also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and transcriptional coactivator associated with p53.
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The
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