jtitle=Acta Paediatrica,ACTA PAEDIATRICA缩写

中科院张老师

于 2021-05-30 15:41:17 发布

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文章标签： jtitle=Acta Paediatrica

一项针对芬兰全国登记的儿童研究发现，低出生体重、早产、新生儿重症监护等因素与反应性依恋障碍存在关联。低出生体重小于2500克的孩子患病几率增加，而出生体重4000-4499克的则较低。研究还显示，妊娠32周以下、诱导分娩及新生儿监护期间的诊断风险上升。这些发现有助于深化对儿童反应性依恋障碍发展机制的理解。

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Abstract:

AIM:To examine the association between several perinatal and obstetric risk factors and reactive attachment disorder in children diagnosed in specialised services.

METHODS:In this nested case-control study, 614 cases with reactive attachment disorder and 2423 controls matched with age and sex were identified from Finnish national registers. Conditional logistic regression was used to examine the association between a number of perinatal risk factors and reactive attachment disorder.

RESULTS:In the adjusted analysis, a low birthweight of <2500 g was associated with an increased odds of reactive attachment disorder, with an odds ratio (OR) of 1.96 and 95% confidence interval (CI) of 1.17, 3.30 and a birthweight of 4000-4499 grams was associated with decreased odds OR 0.49 (95% CI 0.31, 0.75). The odds for being diagnosed with reactive attachment disorder increased with a gestational age of <32 weeks OR 3.72 (95% CI 1.52, 9.10), induced labour OR 1.34 (95% CI 1.03, 1.75) and monitoring in a neonatal intensive care unit (NICU) OR 1.67 (95% CI 1.09, 2.55).

CONCLUSION:We found associations between low birthweight, preterm birth, NICU admission and reactive attachment disorder. The findings add to the current literature on the understanding of the development of reactive attachment disorder in children.