<Paper reading>总

paper0002
  • apply principal component analysis to the wavelet correlation matrix to produce frequency-specific eigenimages
  • 1/f property
    引用0069: Wavelets and functional magnetic resonance imaging of the human brain

Depression uncouples brain hate circuit

  • Significant correlation between two ROIs may be spurious, that is, a by-product of the correlations of the two ROIs with a third region. To find out whether the correlation for the two ROIs is genuine, the third ROI should be kept constant. Statistically, this problem can be tackled by means of a partial correlation test.
  • six communities correspond to six resting-state networks (RSN)
    • default mode network (RSN1) :
      -ACG(Anterior cingulate gyrus)
      -ANG(Angular gyrus)
      -REC(Rectus gyrus)
      -PCG(Posterior cingulate gyrus)
      -SFGmed(Superior frontal gyrus (medial))
      -ORBmed(Orbitofrontal cortex (medial))
      -SFGdor(Superior frontal gyrus (dorsal))
      -MTG(Middle temporal gyrus)
      -TPOmid(Temporal pole (middle))
      -PCUN(Precuneus)
    • attention network (RSN2):
      -SPG(Superior parietal gyrus)
      -ORBsup(Orbitofrontal cortex (superior))
      -MFG(Middle frontal gyrus)
      -ORBinf(Orbitofrontal cortex (inferior))
      -IFGtriang(Inferior frontal gyrus (triangular))
      -ORBmid(Orbitofrontal cortex (middle))
      -IPL(Inferior parietal lobule)
      -IFGoperc(Inferior frontal gyrus (opercula))
    • visual recognition network (RSN3) :
      -LING(Lingual gyrus)
      -IOG(Inferior occipital gyrus)
      -FFG(Fusiform gyrus)
      -CUN(Cuneus)
      -CAL(Calcarine cortex)
      -SOG(Superior occipital gyrus)
      -MOG(Middle occipital gyrus)
    • auditory network (RSN4):
      -STG(Superior temporal gyrus)
      -SMG(Supramarginal gyrus)
      -ROL(Rolandic operculum)
      -HES(Heschl gyrus)
      -INS(Insula)
      -TPOsup(Temporal pole (superior))
    • sensory-motor areas (RSN5):
      -PreCG(Precentral gyrus)
      -PCL(Paracentral lobule)
      -PoCG(Postcentral gyrus)
      -SMA(Supplementary motor area)
    • subcortical network (RSN6):
      -OLF(Olfactory)
      -THA(Thalamus)
      -PUT(Putamen)
      -HIP(Hippocampus)
      -CAU(Caudate)
      -AMYG(Amygdala)
      -MCG(Middle cingulate gyrus)
      -ITG(Inferior temporal gyrus)
      -PHG(Parahippocampal gyrus)
      -PAL(Pallidum)

<201707 Human Brain Mapping> Dynamic brain connectivity is a better predictor of PTSD than static connectivity

  • we test the hypothesis that subjects with post-traumatic stress disorder (PTSD) are characterized by reduced temporal variability of brain connectivity compared to matched healthy controls.
  • Static functional connectivity (FC; nondirectional zero-lag correlation) and static effective connectivity (EC; directional time-lagged relationships) were obtained over the entire brain using conventional models.
  • Dynamic FC and dynamic EC were estimated by letting the conventional models to vary as a function of time.
  • Our findings support our hypothesis that PTSD subjects have stronger static connectivity, but reduced temporal variability of connectivity.
  • For obtaining DFC(dynamic FC), we employed moving-windowed Pearson’s correlation with window length being determined adaptively by the augmented Dickey–fuller unit root test (ADF test)
  • For obtaining DEC(dynamic EC), we employed dynamic Granger causality (DGC) while correlation-purged Granger causality (CPGC) was used as the static EC (SEC) measure.
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