今天在调试aspx程序时遇到这样的错误，不过错误已经得到解决，请看...
//以下是错误信息－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－

ASP.NET Error: Failed to access IIS metabase
This error showed up prior to the error "Mutex cannot be created" which I descirbed in my last post. I wrote down this to help other poor guys saving their poor time.
The more complete error message is as following:
Failed to access IIS metabase.
Description: An unhandled exception occurred during the execution of the
current web request.
Please review the stack trace for more information about the error and
where it originated in the code.

Exception Details: System.Web.Hosting.HostingEnvironmentException:
Failed to access IIS metabase.

The process account used to run ASP.NET must have read access to the IIS
metabase (e.g. IIS://servername/W3SVC).
//以下是解决方法－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
1.进入ＤＯＳ命令行
2.cd /
3.cd c:/windows/microsoft.net/framework/v2.0.50727
4.然后执行命令 aspnet_regiis -ga administrator //注：administrator为当前登录用户名
5.aspnet_regiis -i -enable
6.net stop iisadmin
7.net start w3svc
//对了说一下，aspnet_regiis.exe这个程序是在c:/windows/microsoft.net/framework/v2.0.50727目录下的，如果你的不是windows xp sp2，那么请您搜寻该程序，只要执行相同的命令即可.