20、生物系统振荡与控制：从建模到应用

生物系统振荡与控制：从建模到应用

1. 生物振荡模拟

在生物系统中，cAMP振荡网络模拟是一个重要的研究领域。使用Gillespie直接方法进行模拟时，会根据不同的反应编号对相关物质的浓度进行更新。以下是Python代码示例：

if reaction == 7:
    REGA = REGA - 1
elif reaction == 8:
    icAMP = icAMP + 1
elif reaction == 9:
    icAMP = icAMP - 1
elif reaction == 10:
    ecAMP = ecAMP + 1
elif reaction == 11:
    ecAMP = ecAMP - 1
elif reaction == 12:
    CAR1 = CAR1 + 1
elif reaction == 13:
    CAR1 = CAR1 - 1
else:
    print(reaction, 'Wrong reaction number!')

time_current = time_current + tau

if time_record < time_current:
    data_idx = data_idx + 1
    species_all[data_idx, :] = np.array([time_current, ACA, PKA, ERK2, REGA, icAMP, ecAMP, CAR1])
    time_record = time_record + dt_record
    print(time_record)