北京大学生物信息学-第二周-序列比对

序列比对中的基本概念

• B iology
  – What is the biological question or problem?
• D ata
  – What is the input data?
  – What other supportive data can be used?
• M odel
  – How is the problem formulated computationally?
  – Or, what’s the data model?
• A lgorithm
  – What is the computational algorithm?
  – How about its performance/limitation?

Sequence Alignment:
The purpose of a sequence alignment is to line up all residues in the inputted sequence(s) for maximal level of similarity, in the sense of their functional or evolutionary relationship.
序列比对的目的是将输入序列中国的所有残基按其功能或进化关系排列，以获得最大程度的相似性。
序列比对：https://www.ebi.ac.uk/Tools/psa/

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